Patricia M LoRusso Selected Research

EC 0489

2/2011

Reducing undesirable hepatic clearance of a tumor-targeted vinca alkaloid via novel saccharopeptidic modifications.

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Patricia M LoRusso Research Topics

Disease

87	Neoplasms (Cancer) 11/2023 - 02/2002
13	Breast Neoplasms (Breast Cancer) 03/2018 - 07/2010
12	Neutropenia 10/2017 - 09/2005
8	Melanoma (Melanoma, Malignant) 01/2021 - 02/2004
7	Thrombocytopenia (Thrombopenia) 05/2017 - 05/2012
5	Diarrhea 01/2022 - 07/2010
4	Nausea 01/2022 - 02/2012
4	Febrile Neutropenia 01/2017 - 06/2014
3	Fatigue 01/2022 - 12/2010
3	Fever (Fevers) 01/2022 - 01/2017
3	Triple Negative Breast Neoplasms 01/2021 - 01/2015
3	Disease Progression 01/2017 - 02/2012
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 12/2010 - 05/2003
2	Vomiting 01/2022 - 01/2019
2	Anemia 01/2020 - 03/2015
2	Dehydration (Water Stress) 01/2019 - 01/2015
2	Gastrointestinal Neoplasms (Gastrointestinal Cancer) 01/2019 - 12/2018
2	Colorectal Neoplasms (Colorectal Cancer) 01/2019 - 12/2010
2	Cardiotoxicity 03/2018 - 08/2008
2	Exanthema (Rash) 04/2016 - 05/2003
2	Neoplasm Metastasis (Metastasis) 03/2015 - 04/2013
2	Lung Neoplasms (Lung Cancer) 04/2014 - 05/2003
2	Basal Cell Carcinoma (Rodent Ulcer) 01/2013 - 09/2009
2	Medulloblastoma 04/2011 - 09/2009
2	Hypersensitivity (Allergy) 09/2005 - 05/2003
1	Prostatic Neoplasms (Prostate Cancer) 01/2023
1	Aseptic Meningitis 01/2022
1	Adenocarcinoma 01/2021
1	Bites and Stings (Sting) 01/2021
1	Rare Diseases (Rare Disease) 01/2021

Drug/Important Bio-Agent (IBA)

9	Ado-Trastuzumab EmtansineIBA 03/2018 - 10/2011
8	Docetaxel (Taxotere)FDA Link 01/2017 - 06/2008
6	Monoclonal AntibodiesIBA 01/2018 - 07/2010
5	Biomarkers (Surrogate Marker)IBA 11/2020 - 06/2014
5	Proteins (Proteins, Gene)FDA Link 01/2020 - 04/2013
5	Trastuzumab (Herceptin)FDA Link 03/2018 - 10/2011
5	ErbB Receptors (EGF Receptor)IBA 04/2016 - 05/2003
5	Immunoconjugates (Immunoconjugate)IBA 09/2015 - 10/2011
4	Paclitaxel (Taxol)FDA LinkGeneric 12/2021 - 10/2011
4	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2021 - 08/2007
4	AZD 6244IBA 10/2017 - 02/2013
4	Lapatinib (GW572016)FDA Link 01/2017 - 06/2008
4	human ERBB2 proteinIBA 09/2015 - 05/2012
4	HhAntag691IBA 01/2013 - 09/2009
3	DNA (Deoxyribonucleic Acid)IBA 11/2023 - 08/2015
3	AntibodiesIBA 01/2022 - 12/2010
3	AntigensIBA 01/2022 - 07/2010
3	veliparibIBA 01/2021 - 01/2015
3	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2021 - 01/2015
3	Aurora Kinase AIBA 01/2019 - 02/2016
3	Cytotoxins (Cytolysins)IBA 01/2018 - 01/2009
3	temsirolimus FDA Link 10/2017 - 02/2013
3	Erlotinib Hydrochloride (CP 358,774)FDA Link 10/2017 - 02/2013
3	Gemcitabine FDA Link 05/2017 - 03/2015
3	pertuzumabIBA 03/2016 - 10/2011
3	Irinotecan (Camptosar)FDA LinkGeneric 01/2016 - 02/2012
2	olaparibIBA 01/2023 - 01/2021
2	cediranib (AZD2171)IBA 01/2023 - 01/2021
2	Protein Isoforms (Isoforms)IBA 01/2021 - 09/2017
2	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 01/2021 - 01/2016
2	Immune Checkpoint InhibitorsIBA 01/2021 - 01/2020
2	Phosphotransferases (Kinase)IBA 01/2020 - 03/2010
2	Lipase (Acid Lipase)FDA Link 01/2020 - 12/2010
2	Cytochrome P-450 CYP3AIBA 01/2020 - 01/2013
2	Antineoplastic Agents (Antineoplastics)IBA 01/2020 - 02/2004
2	MLN 8237IBA 01/2019 - 12/2018
2	Capsules (Microcapsules)IBA 01/2018 - 02/2012
2	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2018 - 11/2010
2	TabletsIBA 01/2018 - 02/2012
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 08/2017 - 01/2005
2	Alanine Transaminase (SGPT)IBA 05/2017 - 01/2015
2	nirogacestatIBA 01/2017 - 01/2015
2	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 01/2017 - 01/2015
2	Messenger RNA (mRNA)IBA 01/2017 - 04/2013
2	taxaneIBA 01/2017 - 06/2014
2	Dacarbazine (DIC)FDA LinkGeneric 01/2017 - 02/2013
2	Cytochrome P-450 CYP2C8IBA 04/2015 - 01/2013
2	KinesinsIBA 04/2015 - 04/2013
2	ixabepilone (BMS 247550)FDA Link 05/2014 - 09/2005
2	Transaminases (Aminotransferases)IBA 05/2012 - 07/2010
2	N-acetylcochinol-O-phosphateIBA 04/2008 - 06/2004
2	Gefitinib (Iressa)FDA Link 06/2003 - 05/2003
1	NucleotidesIBA 11/2023
1	Cell-Free Nucleic AcidsIBA 11/2023
1	itacitinibIBA 01/2022
1	cyclopropapyrroloindoleIBA 01/2022
1	Blood Proteins (Serum Proteins)IBA 01/2022
1	epacadostatIBA 01/2022
1	CytokinesIBA 01/2022
1	parsaclisibIBA 01/2022
1	InterferonsIBA 01/2021
1	ChromatinIBA 01/2021
1	cyclic guanosine monophosphate-adenosine monophosphateIBA 01/2021
1	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 01/2021
1	monomethyl auristatin EIBA 11/2020

Therapy/Procedure

26	Therapeutics 01/2023 - 06/2003
5	Immunotherapy 01/2022 - 08/2015
4	Drug Therapy (Chemotherapy) 01/2020 - 02/2002
4	Intravenous Infusions 04/2015 - 04/2008
1	Castration 01/2023